After taking my fourth weekly shot of methatrexate, I feel week

I took my fourth weekly shot of methatrexate.
I have absolutely no energy. I've been fighting it all day. Anyone else have this problem with the med?

Christie Hagan
C
1 following.
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31 ANSWER

Are you taking folic acid?

Joanne Yang
J

No I didn't know I needed too. So that will help?

Christie Hagan
C

Methotrexate interferes with the way your body breaks down folate. When you take methotrexate, you can develop levels of folate that are lower than normal. This is because methotrexate causes your body to get rid of more folate as waste than usual. This effect causes folate deficiency. Your doctor can prescribe the supplement folic acid to help prevent a folate deficiency. Take 1 mg per day but skip the day you take methotrexate. Talk to a pharmacist.

Lynette Farrell 3 years

I stopped the methotrexate. I couldnt function on it. You have to take folic acid so you can absorb it.

Stacey Bray
S

I take 7.5 mg of methotrexate once a week and 1mg folic acid daily!

Maria Seals
M

Just ran and got some. Shame my Dr didn't let me know.

Christie Hagan
C

Thank you

Christie Hagan
C

The ones I bought say 400 mcg

Christie Hagan
C

I started with 5mg, it will help with the nausea too. Normally they are prescribed together

Stacey Bray
S

What dose of metho do you take? Mg wise, is is pills or injection?

Stacey Bray
S

4 ml

Christie Hagan
C

Injection sorry

Christie Hagan
C

Thats a low does, my metho started at 25 mg once a week and my folic acid was 5 mg daily. You may not need the folic acid for the injections. It would be wise to ask your doc. I was told it helps rhe metho absorb better when taken orally

Stacey Bray
S

I definitely will be calling them. Thanks

Christie Hagan
C

I have the same issue. It drains me out of energy that the next day I don't feel like getting up from bed. I take it before sleeping. Then severe fatigue causes depression

Pia Byrd
P

Yes it does! I've been extremely sensitive to the side effects of mtx. Nausea was horrible and he has me take atarax two hours before. It took care of it. Now on to the rest of the side effects!?!

Christie Hagan 3 years

Priyanka Shirma have you tried taking in the morning instead of evenings... I take methoblastin 20mg every Friday morning and folic acid 5mg twice a week

Susy Lindsay 3 years

Yes I dont do the shots but the oral pill and get fatigued a lot

Erika Diamond
E

I take tablets 15 mg once a week (this is week 6) and I am exhausted for a couple of days after I take it. Haven't felt any benefits yet. My Dr prescribed Folic Acid to go along with it. Not sure if you need Folic Acid if you are getting injections though.

Nick Steele
N

my perscription says take folic acid for 5 days none on day of methotrexate and none day after makes me feel sick after i take methotrexate

Craig Hendricks
C

I also had an issue with fatigue, nausea, dizziness, and heart palpitations. And yes depression too. I changed my diet and I'm much better. Energy like a teenager again. It's great.

April Rucker
A

What changes did you make to your diet?

Mary Washburn 3 years

I feel run down, stomach pain, headache. No more nausea thank God.

Christie Hagan
C

i take stomach pills twice a day helps alot

Craig Hendricks
C

Make sure you're taking 1mg of Folic acid every day. To answer your question, I felt like I had the Flu for two to three days after every dose. Thank God it gradually got better. After three months it was gone, but I still take Folic acid daily.... Sg......

Terrye Cochran
T

Thanks for the info Terrye. That's exactly how I feel for 2-3 days after my weekly dose. Glad to hear it subsided for you. Hoping the same happens for me soon. Week 6 on 15mg / week for me. 1 mg Folic Acid daily.

Nick Steele 3 years

It gets better. But I'm a little over a year in and it's manageable but not gone.

Julie Hooker
J

My Doctor says to take Folic Acid EVERY day..... Sg....

Terrye Cochran
T

Mine too

Julie Hooker 3 years

I also take 20mg of Prilocek daily.... Sg.....

Terrye Cochran
T

i take sandoz rabeprazole 10 mg for my stomack last bottle said 2 once a day one before said 1 twice a day

Craig Hendricks
C

When I first started the Methotrexate, I loaded up on vitamins, especially ones that boost your energy. Also, I would take 600mg of Ibuprofen, followed by 1000mg of acetaminophen five to six hours later. Also, a close friend told me he had great success with medical cannabis..... Sg.......

Terrye Cochran
T

Keep in mind it is a form of chemo. I gave myself injections, took folic acid and Xx? Can't remember for the nausea bit it worked. Talk to you doctors .

It is a tough drug, meant to be to go after your immune system and try to shut down disease. It was too much for me- got shingles several times- immune system shot!

Farrell Hilton
F

hello ladies does any one know if accupuncture helps with osteoarthritis need help please urgent

Amalia Weston
A

Yes, after the six week's dose I was so lethargic. Dr took me off it. I am seeing a new Rheumy March 9th. We will see about Biologics. Mtx is horrible and toxic. I am convinced it is a method for slow death.

Karen Calloway
K

I did with pills got off of them all I wanted to do was going to bed

Elena Malone
E

some of the side effects to the meds are worse than what we have to take them for sometimes, I was on Morphine for years and even though a little excessive one side effect was death!

Tez Mcnamara
T